The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis

BACKGROUND AND OBJECTIVE: The impact of liver cirrhosis on the activity of UDP-glucuronosyltransferases (UGTs) is currently not well characterized. We investigated the glucuronidation capacity and glucuronide accumulation in patients with liver cirrhosis. METHODS: We administered the Basel phenotypi...

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Detalles Bibliográficos
Autores principales: Duthaler, Urs, Bachmann, Fabio, Ozbey, Agustos C., Umehara, Kenichi, Parrott, Neil, Fowler, Stephen, Krähenbühl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386950/
https://www.ncbi.nlm.nih.gov/pubmed/37328712
http://dx.doi.org/10.1007/s40262-023-01261-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386950/
https://www.ncbi.nlm.nih.gov/pubmed/37328712
http://dx.doi.org/10.1007/s40262-023-01261-3

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