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Can coenzyme Q10 alleviate the toxic effect of fenofibrate on skeletal muscle?

Fenofibrate (FEN) is an antilipidemic drug that increases the activity of the lipoprotein lipase enzyme, thus enhancing lipolysis; however, it may cause myopathy and rhabdomyolysis in humans. Coenzyme Q10 (CoQ10) is an endogenously synthesized compound that is found in most living cells and plays an...

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Detalles Bibliográficos
Autores principales: El-Bassouny, Dalia R., Mansour, Alyaa A., Ellakkany, Amany S., Ayuob, Nasra N., AbdElfattah, Amany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386954/
https://www.ncbi.nlm.nih.gov/pubmed/37270716
http://dx.doi.org/10.1007/s00418-023-02205-5