The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2

The cytokine tumor necrosis factor (TNF) critically regulates the intertwined cell death and pro-inflammatory signaling pathways of dendritic cells (DCs) via ubiquitin modification of central effector molecules, but the intrinsic molecular switches deciding on either pathway are incompletely defined...

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Detalles Bibliográficos
Autores principales: Harit, Kunjan, Bhattacharjee, Rituparna, Matuschewski, Kai, Becker, Jennifer, Kalinke, Ulrich, Schlüter, Dirk, Nishanth, Gopala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387084/
https://www.ncbi.nlm.nih.gov/pubmed/37516734
http://dx.doi.org/10.1038/s41419-023-06014-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387084/
https://www.ncbi.nlm.nih.gov/pubmed/37516734
http://dx.doi.org/10.1038/s41419-023-06014-5

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