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Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development

WDR11, a gene associated with Kallmann syndrome, is important in reproductive system development but molecular understanding of its action remains incomplete. We previously reported that Wdr11-deficient embryos exhibit defective ciliogenesis and developmental defects associated with Hedgehog (HH) si...

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Detalles Bibliográficos
Autores principales: Lee, Jiyoung, Kim, Yeonjoo, Ataliotis, Paris, Kim, Hyung-Goo, Kim, Dae-Won, Bennett, Dorothy C., Brown, Nigel A., Layman, Lawrence C., Kim, Soo-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387110/
https://www.ncbi.nlm.nih.gov/pubmed/37516749
http://dx.doi.org/10.1038/s41598-023-38017-9