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RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation

Mammalian development is precisely controlled by cell differentiation. Identifying new regulators and investigating their interactions provide insight into genetic networks defining pre-implantation development. We established a knockout mouse model of Dis3, an exosome associated ribonuclease. Homoz...

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Detalles Bibliográficos
Autores principales: Wu, Di, Dean, Jurrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387129/
https://www.ncbi.nlm.nih.gov/pubmed/36724075
http://dx.doi.org/10.1016/j.celrep.2023.112047