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Moringa oleifera Leaves Extract Ameliorates Doxorubicin-Induced Cardiotoxicity via Its Mitochondrial Biogenesis Modulatory Activity in Rats

BACKGROUND: Doxorubicin, an anthracycline class of anticancer, is an effective chemotherapeutic agent with serious adverse effects, mainly cardiotoxicity. Several possible causes of doxorubicin cardiotoxicity are increased oxidative stress, nucleic acid and protein synthesis inhibition, cardiomyocyt...

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Detalles Bibliográficos
Autores principales: Patintingan, Cyntia Gracesella, Louisa, Melva, Juniantito, Vetnizah, Arozal, Wawaimuli, Hanifah, Silmi, Wanandi, Septelia Inawati, Thandavarayan, Rajarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387274/
https://www.ncbi.nlm.nih.gov/pubmed/37525636
http://dx.doi.org/10.2147/JEP.S413256