Ceramide compensation by ceramide synthases preserves retinal function and structure in a retinal dystrophy mouse model

Increasing evidence has supported the role of ceramide as a mediator of photoreceptor dysfunction or cell death in ceramide accumulation and deficiency contexts. TLCD3B, a non-canonical ceramide synthase, was previously identified in addition to the six canonical ceramide synthases (CerSs), and the...

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Detalles Bibliográficos
Autores principales: Qian, Xinye, Srinivasan, Tanmay, He, Jessica, Lu, Jiaxiong, Jin, Yan, Gu, Haiwei, Chen, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387349/
https://www.ncbi.nlm.nih.gov/pubmed/37466006
http://dx.doi.org/10.1242/dmm.050168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387349/
https://www.ncbi.nlm.nih.gov/pubmed/37466006
http://dx.doi.org/10.1242/dmm.050168

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