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Case report: ALK D1225N missense mutation in lung adenocarcinoma responds to tyrosine kinase inhibitors

ALK gene missense mutations are conventionally considered non-driver mutations without pathological significance, and therefore, there is a lack of effective target drugs against them. The standard treatment option for patients with ALK missense mutations is chemotherapy with or without antiangiogen...

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Detalles Bibliográficos
Autores principales: Chen, Jianxin, Wang, Junhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387523/
https://www.ncbi.nlm.nih.gov/pubmed/37529699
http://dx.doi.org/10.3389/fphar.2023.1190447