Cargando…

Knockdown of 11β-hydroxysteroid dehydrogenase type 1 alleviates LPS-induced myocardial dysfunction through the AMPK/SIRT1/PGC-1α pathway

Sepsis-induced myocardial dysfunction is primarily accompanied by severe sepsis, which is associated with high morbidity and mortality. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), encoded by Hsd11b1, is a reductase that can convert inactive cortisone into metabolically active cortisol, but t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Dongmei, Luo, Lingli, Zeng, Hanjie, Zhang, Zheng, Huang, Min, Zhou, Suming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387747/ https://www.ncbi.nlm.nih.gov/pubmed/37246430 http://dx.doi.org/10.7555/JBR.36.20220212

Ejemplares similares

11β-Hydroxysteroid dehydrogenase type 1 amplifies inflammation in LPS-induced THP-1 cells
por: Luo, Lingli, et al.
Publicado: (2023)

Diallyl trisulfide alleviates chemotherapy sensitivity of ovarian cancer via the AMPK/SIRT1/PGC1α pathway
por: Wang, Zhaojun, et al.
Publicado: (2022)

Abdominal Massage Alleviates Skeletal Muscle Insulin Resistance by Regulating the AMPK/SIRT1/PGC-1α Signaling Pathway
por: Han, Yiran, et al.
Publicado: (2021)

The increased ratio of 11β-hydroxysteroid dehydrogenase type 1 versus 11β-hydroxysteroid dehydrogenase type 2 in chronic periodontitis irrespective of obesity
por: Nakata, Takaya, et al.
Publicado: (2016)

Effects of Cellular 11β-hydroxysteroid Dehydrogenase 1 on LPS-induced Inflammatory Responses in Synovial Cell Line, SW982
por: Cho, Young Sik, et al.
Publicado: (2017)

11β-Hydroxysteroid Dehydrogenase 2 in Preeclampsia
por: Kosicka, Katarzyna, et al.
Publicado: (2016)

Role of 11β-hydroxysteroid dehydrogenase type 1 in the development of atopic dermatitis
por: Lee, Noo Ri, et al.
Publicado: (2020)

PARP-1 and SIRT-1 are Interacted in Diabetic Nephropathy by Activating AMPK/PGC-1α Signaling Pathway
por: Zhu, Hengmei, et al.
Publicado: (2021)

The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats
por: Nakata, Takaya, et al.
Publicado: (2016)

11β-Hydroxysteroid Dehydrogenases and Hypertension in the Metabolic Syndrome
por: Bailey, Matthew A.
Publicado: (2017)

Effect of Glucocorticoid and 11β-Hydroxysteroid-Dehydrogenase Type 1 (11β-HSD1) in Neurological and Psychiatric Disorders
por: Dodd, Seetal, et al.
Publicado: (2022)

An inhibitor of 11-β hydroxysteroid dehydrogenase type 1 (PF915275) alleviates nonylphenol-induced hyperadrenalism and adiposity in rat and human cells
por: Chang, Ling-Ling, et al.
Publicado: (2018)

Cumulative Effect of Cardiovascular Risk Factors on Regulation of AMPK/SIRT1-PGC-1α-SIRT3 Pathway in the Human Erectile Tissue
por: Pereira, Andressa S., et al.
Publicado: (2020)

Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle
por: Palacios, Orsolya M., et al.
Publicado: (2009)

Cortisol Release From Adipose Tissue by 11β-Hydroxysteroid Dehydrogenase Type 1 in Humans
por: Stimson, Roland H., et al.
Publicado: (2009)

Discovery of Adamantyl Heterocyclic Ketones as Potent 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors
por: Su, Xiangdong, et al.
Publicado: (2011)

Changing glucocorticoid action: 11β-Hydroxysteroid dehydrogenase type 1 in acute and chronic inflammation
por: Chapman, Karen E., et al.
Publicado: (2013)

Adamantyl carboxamides and acetamides as potent human 11β-hydroxysteroid dehydrogenase type 1 inhibitors
por: Su, Xiangdong, et al.
Publicado: (2012)

11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet
por: Johnson, Jethro S, et al.
Publicado: (2016)

Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
por: Deng, Xu, et al.
Publicado: (2022)

11β-Hydroxysteroid Dehydrogenase Type 1 as a Potential Treatment Target in Cardiovascular Diseases
por: Kupczyk, Daria, et al.
Publicado: (2022)

Thioredoxin-1 Promotes Mitochondrial Biogenesis Through Regulating AMPK/Sirt1/PGC1α Pathway in Alzheimer's Disease
por: Jia, Jinjing, et al.
Publicado: (2023)

Chlorogenic Acid Alleviates LPS-Induced Inflammation and Oxidative Stress by Modulating CD36/AMPK/PGC-1α in RAW264.7 Macrophages
por: Gu, Tiantian, et al.
Publicado: (2023)

Myostatin Knockout Affects Mitochondrial Function by Inhibiting the AMPK/SIRT1/PGC1α Pathway in Skeletal Muscle
por: Gu, Mingjuan, et al.
Publicado: (2022)

Empagliflozin attenuates doxorubicin-induced cardiotoxicity by activating AMPK/SIRT-1/PGC-1α-mediated mitochondrial biogenesis
por: Chen, Meicong
Publicado: (2023)

Idiopathic intracranial hypertension, hormones, and 11β-hydroxysteroid dehydrogenases
por: Markey, Keira A, et al.
Publicado: (2016)

Cortisol, Hypertension and Obesity: The Role of 11β-Hydroxysteroid Dehydrogenase
por: Stewart, Paul M
Publicado: (1998)

Sirtuin 3 (SIRT3) maintains bone homeostasis by regulating AMPK-PGC-1β axis in mice
por: Huh, Jeong-Eun, et al.
Publicado: (2016)

11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) mediates insulin resistance through JNK activation in adipocytes
por: Peng, Kesong, et al.
Publicado: (2016)

Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1α signaling
por: Huang, Bingqing, et al.
Publicado: (2014)

Glycyrrhizic Acid Prevents Diabetic Nephropathy by Activating AMPK/SIRT1/PGC-1α Signaling in db/db Mice
por: Hou, Shaozhang, et al.
Publicado: (2017)

The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway
por: Yang, Xuping, et al.
Publicado: (2020)

D-allulose ameliorates adiposity through the AMPK-SIRT1-PGC-1α pathway in HFD-induced SD rats
por: Lee, Geum-Hwa, et al.
Publicado: (2021)

Atractylenolide III Improves Mitochondrial Function and Protects Against Ulcerative Colitis by Activating AMPK/SIRT1/PGC-1α
por: Han, Jieru, et al.
Publicado: (2022)

Variants of 11β-hydroxysteroid dehydrogenase (HSD11B) gene type 1 and 2 in Chinese obese adolescents
por: Chun, Zou Chao
Publicado: (2013)

A novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis
por: Bujalska, I J, et al.
Publicado: (2008)

11β-Hydroxysteroid Dehydrogenase Type 1 Regulates Glucocorticoid-Induced Insulin Resistance in Skeletal Muscle
por: Morgan, Stuart A., et al.
Publicado: (2009)

Tissue-Specific Increases in 11β-Hydroxysteroid Dehydrogenase Type 1 in Normal Weight Postmenopausal Women
por: Andersson, Therése, et al.
Publicado: (2009)

11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis
por: Kipari, Tiina, et al.
Publicado: (2013)

11β-hydroxysteroid dehydrogenase-1 deficiency alters brain energy metabolism in acute systemic inflammation
por: Verma, Manu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pkjacjfa0tomk1jtdg4m11vf28