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Insights into Omicron’s Low Fusogenicity through In Silico Molecular Studies on Spike-Furin Interactions

The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant and its subvariants have a unique set of mutations. Two of those mutations (N679 K and P681 H) reside close to the S1 /S2 furin cleavage site (FCS; 685-686). When these mutations reside together, they exert less-efficie...

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Detalles Bibliográficos
Autores principales: Mondol, Spencer Mark, Hasib, Md, Limon, Md. Belayet Hasan, Alam, A S M Rubayet Ul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387760/
https://www.ncbi.nlm.nih.gov/pubmed/37529484
http://dx.doi.org/10.1177/11779322231189371