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Inhibition of TRPV4 attenuates ferroptosis against LPS-induced ALI via Ca(2+) pathway

Acute lung injury (ALI) is an inflammation of the lungs with high incidence rate and mortality. Ferroptosis is a new cell death, which has influence in body organs. Transient receptor potential vanillin-4 (TRPV4) channel is a key mediator of Ca(2+), its activation induces ferroptosis. The purpose of...

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Detalles Bibliográficos
Autores principales: CAI, Junying, XU, Guohai, LIN, Yue, ZHOU, Bin, LUO, Zhenzhong, YU, Shuchun, LU, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific and Technological Research Council of Turkey (TUBITAK) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387841/
https://www.ncbi.nlm.nih.gov/pubmed/37529798
http://dx.doi.org/10.55730/1300-0152.2632