EGFR blocker lapatinib inhibits the synthesis of matrix metalloproteinases from synovial fibroblasts

BACKGROUND/AIM: Epidermal growth factor receptor (EGFR) family members and their associated ligands may be related to bone and joint destruction in rheumatoid arthritis. Matrix metalloproteinases are responsible for joint and bone tissue degradation. This study is intended to investigate the effect...

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Detalles Bibliográficos
Autores principales: YALÇIN KEHRİBAR, Demet, EMMUNGİL, Hakan, BAŞAK TÜRKMEN, Neşe, ÇİFTÇİ, Osman, SALVA, Emine, ÖZGEN, Metin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific and Technological Research Council of Turkey (TUBITAK) 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387858/
https://www.ncbi.nlm.nih.gov/pubmed/36326383
http://dx.doi.org/10.55730/1300-0144.5442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387858/
https://www.ncbi.nlm.nih.gov/pubmed/36326383
http://dx.doi.org/10.55730/1300-0144.5442

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