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EGFR blocker lapatinib inhibits the synthesis of matrix metalloproteinases from synovial fibroblasts
BACKGROUND/AIM: Epidermal growth factor receptor (EGFR) family members and their associated ligands may be related to bone and joint destruction in rheumatoid arthritis. Matrix metalloproteinases are responsible for joint and bone tissue degradation. This study is intended to investigate the effect...
Autores principales: | YALÇIN KEHRİBAR, Demet, EMMUNGİL, Hakan, BAŞAK TÜRKMEN, Neşe, ÇİFTÇİ, Osman, SALVA, Emine, ÖZGEN, Metin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Scientific and Technological Research Council of Turkey (TUBITAK)
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387858/ https://www.ncbi.nlm.nih.gov/pubmed/36326383 http://dx.doi.org/10.55730/1300-0144.5442 |
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