Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate

Human fetal cytochrome P450 3A7 (CYP3A7) is involved in both xenobiotic metabolism and the estriol biosynthetic pathway. Although much is understood about cytochrome P450 3A4 and its role in adult drug metabolism, CYP3A7 is poorly characterized in terms of its interactions with both categories of su...

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Detalles Bibliográficos
Autores principales: Liu, Jinghan, Kandel, Sylvie E., Lampe, Jed N., Scott, Emily E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388207/
https://www.ncbi.nlm.nih.gov/pubmed/37392852
http://dx.doi.org/10.1016/j.jbc.2023.104993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388207/
https://www.ncbi.nlm.nih.gov/pubmed/37392852
http://dx.doi.org/10.1016/j.jbc.2023.104993

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