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Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate
Human fetal cytochrome P450 3A7 (CYP3A7) is involved in both xenobiotic metabolism and the estriol biosynthetic pathway. Although much is understood about cytochrome P450 3A4 and its role in adult drug metabolism, CYP3A7 is poorly characterized in terms of its interactions with both categories of su...
Autores principales: | Liu, Jinghan, Kandel, Sylvie E., Lampe, Jed N., Scott, Emily E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388207/ https://www.ncbi.nlm.nih.gov/pubmed/37392852 http://dx.doi.org/10.1016/j.jbc.2023.104993 |
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