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Striatal mGlu(5)-mediated synaptic plasticity is independently regulated by location-specific receptor pools and divergent signaling pathways

Metabotropic glutamate receptor 5 (mGlu(5)) is widely expressed throughout the central nervous system and is involved in neuronal function, synaptic transmission, and a number of neuropsychiatric disorders such as depression, anxiety, and autism. Recent work from this lab showed that mGlu(5) is one...

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Detalles Bibliográficos
Autores principales: Jong, Yuh-Jiin I., Izumi, Yukitoshi, Harmon, Steven K., Zorumski, Charles F., ÓMalley, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388212/
https://www.ncbi.nlm.nih.gov/pubmed/37354970
http://dx.doi.org/10.1016/j.jbc.2023.104949