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PARP1 and POLD2 as prognostic biomarkers for multiple myeloma in autologous stem cell transplant

Multiple Myeloma (MM) is an incurable plasma cell malignancy often treated by autologous stem cell transplant (ASCT). Clinical response to ASCT has been associated with DNA repair efficiency. Here we interrogated the role of the base excision DNA repair (BER) pathway in MM response to ASCT. Across 4...

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Detalles Bibliográficos
Autores principales: Thomas, Melissa, Li, Junan, King, Kevan, Persaud, Avinash K., Duah, Ernest, Vangundy, Zachary, Hofmeister, Craig C., Lamba, Jatinder K., Tan, Aik Choon, Fridley, Brooke L., Poi, Ming J., Seligson, Nathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388271/
https://www.ncbi.nlm.nih.gov/pubmed/36861411
http://dx.doi.org/10.3324/haematol.2022.282399