The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy

T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is an inhibitory checkpoint receptor that negatively regulates T-cell responses. CD226 competes with TIGIT for binding to the CD155 ligand, delivering a positive signal to the T cell. Here we studied the expression of TIGIT and CD226 in a cohort...

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Detalles Bibliográficos
Autores principales: Arruga, Francesca, Rubin, Marta, Papazoglou, Despoina, Iannello, Andrea, Ioannou, Nikolaos, Moia, Riccardo, Rossi, Davide, Gaidano, Gianluca, Coscia, Marta, Laurenti, Luca, D’Arena, Giovanni, Allan, John N., Furman, Richard R., Vaisitti, Tiziana, Ramsay, Alan G., Deaglio, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Chronic Lymphocytic Leukemia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388274/
https://www.ncbi.nlm.nih.gov/pubmed/36655432
http://dx.doi.org/10.3324/haematol.2022.282177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388274/
https://www.ncbi.nlm.nih.gov/pubmed/36655432
http://dx.doi.org/10.3324/haematol.2022.282177

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