Discovery and Characterization of PROTACs Targeting Tissue Transglutaminase (TG2)

[Image: see text] Tissue transglutaminase (TG2) is a multifunctional enzyme involved in the cross-linking of extracellular matrix proteins, formation of complexes with fibronectin (FN) and integrins, and GTP hydrolysis. TG2 is activated in several pathological conditions, including cancer. We recent...

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Detalles Bibliográficos
Autores principales: Valdivia, Andres, Vagadia, Purav P., Guo, Guangxu, O’Brien, Eilidh, Matei, Daniela, Schiltz, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388319/
https://www.ncbi.nlm.nih.gov/pubmed/37449845
http://dx.doi.org/10.1021/acs.jmedchem.2c01859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388319/
https://www.ncbi.nlm.nih.gov/pubmed/37449845
http://dx.doi.org/10.1021/acs.jmedchem.2c01859

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