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BTRX-246040 Acts Through the Ventrolateral Periaqueductal Gray to Exert Antidepressant-Relevant Actions in Mice

BACKGROUND: BTRX-246040, a nociceptin/orphanin FQ peptide receptor antagonist, is being developed for the treatment of depressive patients. However, the underlying mechanism of this potential antidepressant is still largely unclear. Here, we studied the antidepressant-related actions of BTRX-246040...

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Detalles Bibliográficos
Autores principales: Li, Zhenlong, Xu, Yuanyuan, Li, Rourou, Sheng, Zhenyu, Chen, Xinya, Liu, Xueman, Lee, Chau-Shoun, Peng, Hsien-Yu, Lin, Tzer-Bin, Hsieh, Ming-Chun, Lai, Cheng-Yuan, Wu, Han-Fang, Chou, Dylan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388391/
https://www.ncbi.nlm.nih.gov/pubmed/37279653
http://dx.doi.org/10.1093/ijnp/pyad027