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Leukocyte- and platelet-rich fibrin in endoscopic endonasal skull base reconstruction: study protocol for a multicenter prospective, parallel-group, single-blinded randomized controlled non-inferiority trial

BACKGROUND: Recent advances in endoscopic endonasal transsphenoidal approaches (EETA) for skull base lesions have resulted in a significant increase in extent and complexity of skull base defects, demanding more elaborate and novel reconstruction techniques to prevent cerebrospinal fluid (CSF) leaka...

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Detalles Bibliográficos
Autores principales: Coucke, Birgit, Van Hoylandt, Anaïs, Jorissen, Mark, Meulemans, Jeroen, Decramer, Thomas, van Loon, Johannes, Vander Poorten, Vincent, Theys, Tom, Van Gerven, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388446/
https://www.ncbi.nlm.nih.gov/pubmed/37525278
http://dx.doi.org/10.1186/s13063-023-07492-w