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SALL4 promotes angiogenesis in gastric cancer by regulating VEGF expression and targeting SALL4/VEGF pathway inhibits cancer progression

BACKGROUND: Spalt-like protein 4 (SALL4) is a stemness-related transcription factor whose abnormal re-expression contributes to cancer initiation and progression. However, the role of SALL4 in cancer angiogenesis remains unknown. METHODS: Analyses of clinical specimens via TCGA datasets were perform...

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Detalles Bibliográficos
Autores principales: Abouelnazar, Fatma A., Zhang, Xiaoxin, Zhang, Jiahui, Wang, Maoye, Yu, Dan, Zang, Xueyan, Zhang, Jiayin, Li, Yixin, Xu, Jing, Yang, Qiurong, Zhou, Yue, Tang, Haozhou, Wang, Yanzheng, Gu, Jianmei, Zhang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388482/
https://www.ncbi.nlm.nih.gov/pubmed/37525212
http://dx.doi.org/10.1186/s12935-023-02985-9