Exercise-induced irisin improves follicular dysfunction by inhibiting IRE1α-TXNIP/ROS-NLRP3 pathway in PCOS

BACKGROUND: Excessive production of androgen drives oxidative stress (OS) and inflammasome activation in ovarian granulosa cells (GCs). Therefore, the induced follicular developmental disorder is the major cause of infertility in women with polycystic ovary syndrome (PCOS). Exercise-induced upregula...

Descripción completa

Detalles Bibliográficos
Autores principales: Weng, Yajing, Zhang, Yaling, Wang, Daojuan, Wang, Rong, Xiang, Zou, Shen, Shanmei, Wang, Hongwei, Wu, Xiaoke, Wen, Yanting, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388501/
https://www.ncbi.nlm.nih.gov/pubmed/37525261
http://dx.doi.org/10.1186/s13048-023-01242-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388501/
https://www.ncbi.nlm.nih.gov/pubmed/37525261
http://dx.doi.org/10.1186/s13048-023-01242-x

Ejemplares similares