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A meta-analysis of immune-cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes

BACKGROUND: Changes in cell-type composition of tissues are associated with a wide range of diseases and environmental risk factors and may be causally implicated in disease development and progression. However, these shifts in cell-type fractions are often of a low magnitude, or involve similar cel...

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Detalles Bibliográficos
Autores principales: Luo, Qi, Dwaraka, Varun B., Chen, Qingwen, Tong, Huige, Zhu, Tianyu, Seale, Kirsten, Raffaele, Joseph M., Zheng, Shijie C., Mendez, Tavis L., Chen, Yulu, Carreras, Natalia, Begum, Sofina, Mendez, Kevin, Voisin, Sarah, Eynon, Nir, Lasky-Su, Jessica A., Smith, Ryan, Teschendorff, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388560/
https://www.ncbi.nlm.nih.gov/pubmed/37525279
http://dx.doi.org/10.1186/s13073-023-01211-5