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The α(2) Adrenoceptor Agonist and Sedative/Anaesthetic Dexmedetomidine Excites Diverse Neuronal Types in the Ventrolateral Preoptic Area of Male Mice

The unique sedative activities with rapid arousal of dexmedetomidine (Dex) are not fully understood. Growing evidence suggests the involvement of the ventrolateral preoptic area (VLPO) in sleep–wake cycle. The major type in the VLPO is sleep-active neurons, inhibited by noradrenaline (NA(−) neurons)...

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Detalles Bibliográficos
Autores principales: Fan, Sumei, Cheng, Xinqi, Zhang, Pingping, Wang, Yuanyin, Wang, Liecheng, Cheng, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388635/
https://www.ncbi.nlm.nih.gov/pubmed/37499170
http://dx.doi.org/10.1177/17590914231191016