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Optimising prednisolone or prednisone replacement in adrenal insufficiency

CONTEXT: Patients with adrenal insufficiency (AI) have a higher mortality than the general population, possibly because of excess glucocorticoid exposure at inappropriate times. The cortisol circadian rhythm is difficult to mimic with twice- or thrice-daily hydrocortisone. Prednisolone is a once-dai...

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Detalles Bibliográficos
Autores principales: Sharma, Angelica, Lazarus, Katharine, Papadopoulou, Deborah, Prabhudev, Hemanth, Tan, Tricia, Meeran, Karim, Choudhury, Sirazum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388668/
https://www.ncbi.nlm.nih.gov/pubmed/37289726
http://dx.doi.org/10.1530/EC-23-0097