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Characterizing the Immune Microenvironment and Neoantigen Landscape of Hürthle Cell Carcinoma to Identify Potential Immunologic Vulnerabilities

Hürthle cell carcinoma (HCC) is a rare type of thyroid cancer with high rates of distant metastasis and recurrence. Along with the scarcity of effective systemic therapies for HCC, these factors contribute to poor clinical outcomes. The immunologic features of HCC are poorly defined and response rat...

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Detalles Bibliográficos
Autores principales: Ganly, Ian, Kuo, Fengshen, Makarov, Vladimir, Dong, Yiyu, Ghossein, Ronald, Xu, Bin, Morris, Luc G.T., Chan, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389111/
https://www.ncbi.nlm.nih.gov/pubmed/37529400
http://dx.doi.org/10.1158/2767-9764.CRC-23-0120