Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes

BACKGROUND: Glucose metabolism, specifically, hexokinase 2 (HK2), has a critical role in rheumatoid arthritis (RA) fibroblast-like synoviocyte (FLS) phenotype. HK2 localizes not only in the cytosol but also in the mitochondria, where it protects mitochondria against stress. We hypothesize that mitoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres, Alyssa, Kang, Sarah, Mahony, Christopher B., Cedeño, Martha, Oliveira, Patricia G., Fernandez-Bustamante, Marta, Kemble, Samuel, Laragione, Teresina, Gulko, Percio S., Croft, Adam P., Sanchez-Lopez, Elsa, Miyamoto, Shigeki, Guma, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389265/
https://www.ncbi.nlm.nih.gov/pubmed/37529037
http://dx.doi.org/10.3389/fimmu.2023.1103231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389265/
https://www.ncbi.nlm.nih.gov/pubmed/37529037
http://dx.doi.org/10.3389/fimmu.2023.1103231

Ejemplares similares