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The 4-(dimethylaminoalkyl)piperazine inhibitors of α-glucosidase: allosteric enzyme inhibition and identification of interacting chemical groups

In continuation of our interest in identifying new α-glucosidase inhibitors with potential to become antidiabetic drugs, this work focuses on the study of 4-(dimethylaminoalkyl)piperazine-1-carbodithioate derivatives as α-glucosidase inhibitors. The eight heterocyclic piperazine-dithiocarbamate comp...

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Detalles Bibliográficos
Autores principales: GHANI, Usman, ASHRAF, Sajda, UL HAQ, Zaheer, KAPLANCIKLI, Zafer Asım, DEMİRCİ, Fatih, ÖZKAY, Yusuf, AFZAL, Sibtain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific and Technological Research Council of Turkey (TUBITAK) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390107/
https://www.ncbi.nlm.nih.gov/pubmed/37529755
http://dx.doi.org/10.55730/1300-0527.3453