Combined intranasal and intramuscular parainfluenza 5-, simian adenovirus ChAdOx1- and poxvirus MVA-vectored vaccines induce synergistically HIV-1-specific T cells in the mucosa

INTRODUCTION: The primary goal of this work is to broaden and enhance the options for induction of protective CD8(+) T cells against HIV-1 and respiratory pathogens. METHODS: We explored the advantages of the parainfluenza virus 5 (PIV5) vector for delivery of pathogen-derived transgenes alone and i...

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Detalles Bibliográficos
Autores principales: Beavis, Ashley C., Wee, Edmund G. -T., Akis Yildirim, Belkis M., Borthwick, Nicola, He, Biao, Hanke, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390215/
https://www.ncbi.nlm.nih.gov/pubmed/37529048
http://dx.doi.org/10.3389/fimmu.2023.1186478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390215/
https://www.ncbi.nlm.nih.gov/pubmed/37529048
http://dx.doi.org/10.3389/fimmu.2023.1186478

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