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Plant-derived PAP proteins fused to immunoglobulin A and M Fc domains induce anti-prostate cancer immune response in mice

In this study, recombinant Fc-fused Prostate acid phosphatase (PAP) proteins were produced in transgenic plants. PAP was fused to immunoglobulin (Ig) A and M Fc domain (PAP-IgA Fc and PAP-IgM Fc), which were tagged to the ER retention sequence KDEL to generate PAP-IgA FcK and PAP-IgM FcK. Agrobacter...

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Detalles Bibliográficos
Autores principales: Kang, Yang Joo, Kim, Deuk-Su, Kim, Seyoung, Seo, Young-Jin, Ko, Kisung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390288/
https://www.ncbi.nlm.nih.gov/pubmed/37037672
http://dx.doi.org/10.5483/BMBRep.2022-0207