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Engineering tRNA abundances for synthetic cellular systems

Routinizing the engineering of synthetic cells requires specifying beforehand how many of each molecule are needed. Physics-based tools for estimating desired molecular abundances in whole-cell synthetic biology are missing. Here, we use a colloidal dynamics simulator to make predictions for how tRN...

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Detalles Bibliográficos
Autores principales: Maheshwari, Akshay J., Calles, Jonathan, Waterton, Sean K., Endy, Drew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390467/
https://www.ncbi.nlm.nih.gov/pubmed/37524714
http://dx.doi.org/10.1038/s41467-023-40199-9