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The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes

Herpes simplex virus 1 (HSV-1) infection and stress responses disrupt transcription termination by RNA Polymerase II (Pol II). In HSV-1 infection, but not upon salt or heat stress, this is accompanied by a dramatic increase in chromatin accessibility downstream of genes. Here, we show that the HSV-1...

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Detalles Bibliográficos
Autores principales: Djakovic, Lara, Hennig, Thomas, Reinisch, Katharina, Milić, Andrea, Whisnant, Adam W., Wolf, Katharina, Weiß, Elena, Haas, Tobias, Grothey, Arnhild, Jürges, Christopher S., Kluge, Michael, Wolf, Elmar, Erhard, Florian, Friedel, Caroline C., Dölken, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390501/
https://www.ncbi.nlm.nih.gov/pubmed/37524699
http://dx.doi.org/10.1038/s41467-023-40217-w