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MAT as a promising therapeutic strategy against triple-negative breast cancer via inhibiting PI3K/AKT pathway

Triple-negative breast cancer (TNBC), a highly aggressive and heterogeneous subtype of breast cancer, lacks effective treatment options. Sophora flavescens Aiton, a Chinese medicinal plant, is often used in traditional Chinese medicine to treat cancer. Matrine (MAT) is an alkaloid extracted from Sop...

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Detalles Bibliográficos
Autores principales: Wei, Shijie, Zhang, Yubao, Ma, Xiaoran, Yao, Yan, Zhou, Qinqin, Zhang, Wenfeng, Zhou, Chao, Zhuang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390516/
https://www.ncbi.nlm.nih.gov/pubmed/37524857
http://dx.doi.org/10.1038/s41598-023-39655-9