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NR1D1 deficiency in the tumor microenvironment promotes lung tumor development by activating the NLRP3 inflammasome

Nuclear receptor Rev-erbα (NR1D1) is a major negative regulator of the circadian clock. Numerous studies have investigated the role of circadian clock-related factors in the tumorigenesis of multiple cancer types, but little is known about the role of NR1D1 in cancer development. In this study, we i...

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Detalles Bibliográficos
Autores principales: Kim, Sun Mi, Jeon, Yoon, Jang, Ji Yun, Lee, Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390518/
https://www.ncbi.nlm.nih.gov/pubmed/37524704
http://dx.doi.org/10.1038/s41420-023-01554-3