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Antibody binding of amyloid beta peptide epimers/isomers and ramifications for immunotherapies and drug development

Extracellular deposition of amyloid beta (Aβ) peptide is a contributing factor of Alzheimer’s disease (AD). Considerable effort has been expended to create effective antibodies, or immunotherapies, targeting Aβ peptides. A few immunotherapies are thought to provide some benefit. It is possible that...

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Detalles Bibliográficos
Autores principales: Readel, Elizabeth R., Patel, Arzoo, Putman, Joshua I., Du, Siqi, Armstrong, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390520/
https://www.ncbi.nlm.nih.gov/pubmed/37524807
http://dx.doi.org/10.1038/s41598-023-38788-1