A diverse ancestrally-matched reference panel increases genotype imputation accuracy in a underrepresented population

Variant imputation, a common practice in genome-wide association studies, relies on reference panels to infer unobserved genotypes. Multiple public reference panels are currently available with variations in size, sequencing depth, and represented populations. Currently, limited data exist regarding...

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Detalles Bibliográficos
Autores principales: Mauleekoonphairoj, John, Tongsima, Sissades, Khongphatthanayothin, Apichai, Jurgens, Sean J., Zimmerman, Dominic S., Sutjaporn, Boosamas, Wandee, Pharawee, Bezzina, Connie R., Nademanee, Koonlawee, Poovorawan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390539/
https://www.ncbi.nlm.nih.gov/pubmed/37524845
http://dx.doi.org/10.1038/s41598-023-39429-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390539/
https://www.ncbi.nlm.nih.gov/pubmed/37524845
http://dx.doi.org/10.1038/s41598-023-39429-3

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