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A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion
T cells play a key role in a variety of immune responses, including infection and cancer. Upon stimulation, naïve CD8+ T cells proliferate and differentiate into a variety of memory and effector cell types; however, failure to clear antigens causes prolonged stimulation of CD8+ T cells, ultimately l...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390540/ https://www.ncbi.nlm.nih.gov/pubmed/37524735 http://dx.doi.org/10.1038/s41540-023-00297-2 |