Cargando…

A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

T cells play a key role in a variety of immune responses, including infection and cancer. Upon stimulation, naïve CD8+ T cells proliferate and differentiate into a variety of memory and effector cell types; however, failure to clear antigens causes prolonged stimulation of CD8+ T cells, ultimately l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ildefonso, Geena V., Finley, Stacey D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390540/ https://www.ncbi.nlm.nih.gov/pubmed/37524735 http://dx.doi.org/10.1038/s41540-023-00297-2

Ejemplares similares

Exhausted phenotype of circulating CD8(+) T cell subsets in hepatitis B virus carriers
por: Jiang, Daixi, et al.
Publicado: (2022)

Regulation of CD8(+) T memory and exhaustion by the mTOR signals
por: Chen, Yao, et al.
Publicado: (2023)

Pregnancy programs epigenetic and transcriptional exhaustion in memory CD8(+) T cells
por: Pollard, Jared, et al.
Publicado: (2023)

Manthan: A Data-Driven Approach for Boolean Function Synthesis
por: Golia, Priyanka, et al.
Publicado: (2020)

A functional subset of CD8(+) T cells during chronic exhaustion is defined by SIRPα expression
por: Myers, Lara M., et al.
Publicado: (2019)

Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models
por: Blanchard, Lucas, et al.
Publicado: (2022)

Author Correction: Regulation of CD8(+) T memory and exhaustion by the mTOR signals
por: Chen, Yao, et al.
Publicado: (2023)

CD38 marks the exhausted CD8(+) tissue-resident memory T cells in hepatocellular carcinoma
por: Reolo, Marie J. Y., et al.
Publicado: (2023)

A Novel Data-Driven Boolean Model for Genetic Regulatory Networks
por: Chen, Leshi, et al.
Publicado: (2018)

Data-Driven Modeling of Breast Cancer Tumors Using Boolean Networks
por: Sgariglia, Domenico, et al.
Publicado: (2021)

Boolean Models of Biological Processes Explain Cascade-Like Behavior
por: Chen, Hao, et al.
Publicado: (2016)

Ineffective treatment of PML with pembrolizumab: Exhausted memory T-cell subsets as a clue?
por: Pawlitzki, Marc, et al.
Publicado: (2019)

CD8(+) T Cell Exhaustion in Cancer
por: Dolina, Joseph S., et al.
Publicado: (2021)

Antigen-driven EGR2 expression is required for exhausted CD8(+) T cell stability and maintenance
por: Wagle, Mayura V., et al.
Publicado: (2021)

Data-driven learning of Boolean networks and functions by optimal causation entropy principle
por: Sun, Jie, et al.
Publicado: (2022)

Immediate Cytotoxicity But Not Degranulation Distinguishes Effector and Memory Subsets of CD8(+) T Cells
por: Wolint, Petra, et al.
Publicado: (2004)

Erratum: Boolean Models of Biological Processes Explain Cascade-Like Behavior
por: Chen, Hao, et al.
Publicado: (2017)

IL-21 in Homeostasis of Resident Memory and Exhausted CD8 T Cells during Persistent Infection
por: Ren, Heather M., et al.
Publicado: (2020)

Distinct Immune Profiles of Exhausted Effector and Memory CD8(+) T Cells in Individuals With Filarial Lymphedema
por: Horn, Sacha, et al.
Publicado: (2021)

Detection of attractors of large Boolean networks via exhaustive enumeration of appropriate subspaces of the state space
por: Berntenis, Nikolaos, et al.
Publicado: (2013)

MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection
por: Stelekati, Erietta, et al.
Publicado: (2022)

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
por: Sarkar, Surojit, et al.
Publicado: (2008)

Sepsis-induced changes in differentiation, maintenance, and function of memory CD8 T cell subsets
por: Heidarian, Mohammad, et al.
Publicado: (2023)

Hypoxia Supports Differentiation of Terminally Exhausted CD8 T Cells
por: Bannoud, Nadia, et al.
Publicado: (2021)

CD39 Expression Identifies Terminally Exhausted CD8(+) T Cells
por: Gupta, Prakash K., et al.
Publicado: (2015)

Fas expression in memory CD8+ T cell subsets augments cellular differentiation and effector function
por: Yamamoto, Tori, et al.
Publicado: (2015)

Boolean reasoning : the logic of Boolean equations
por: Brown, Frank Markham, 1930-
Publicado: (1990)

CD49a Identifies Polyfunctional Memory CD8 T Cell Subsets that Persist in the Lungs After Influenza Infection
por: Reilly, Emma C., et al.
Publicado: (2021)

Boolean logic algebra driven similarity measure for text based applications
por: Abdalla, Hassan I., et al.
Publicado: (2021)

Re-defining T-Cell Exhaustion: Subset, Function, and Regulation
por: Im, Se Jin, et al.
Publicado: (2020)

Dynamic Network Biomarker of Pre-Exhausted CD8(+) T Cells Contributed to T Cell Exhaustion in Colorectal Cancer
por: Hu, Jiaqi, et al.
Publicado: (2021)

Accumulation of exhausted CD8+ T cells in extramammary Paget’s disease
por: Iga, Natsuko, et al.
Publicado: (2019)

TOX transcriptionally and epigenetically programs CD8(+) T cell exhaustion
por: Khan, Omar, et al.
Publicado: (2019)

Helpless Priming Sends CD8(+) T Cells on the Road to Exhaustion
por: Busselaar, Julia, et al.
Publicado: (2020)

Skeletal muscle antagonizes antiviral CD8(+) T cell exhaustion
por: Wu, Jingxia, et al.
Publicado: (2020)

Activation or exhaustion of CD8(+) T cells in patients with COVID-19
por: Rha, Min-Seok, et al.
Publicado: (2021)

Transcriptional regulatory network for the establishment of CD8(+) T cell exhaustion
por: Seo, Wooseok, et al.
Publicado: (2021)

Sex‐bias in CD8 (+) T‐cell stemness and exhaustion in cancer
por: Hussain, Tabinda, et al.
Publicado: (2022)

Strategies to reinvigorate exhausted CD8(+) T cells in tumor microenvironment
por: Guan, Qianting, et al.
Publicado: (2023)

Landscapes and mechanisms of CD8(+) T cell exhaustion in gastrointestinal cancer
por: Ding, Jia-Tong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_01dcvjjt2mikf8sejipvpv3bc5