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Activation of cAMP (EPAC2) signaling pathway promotes hepatocyte attachment

Primary Human Hepatocyte (PHH) remains undefeated as the gold standard in hepatic studies. Despite its valuable properties, partial attachment loss due to the extraction process and cryopreservation remained the main hurdle in its application. We hypothesized that we could overcome the loss of PHH c...

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Detalles Bibliográficos
Autores principales: Helena, Grace Aprilia, Watanabe, Teruhiko, Kato, Yusuke, Shiraki, Nobuaki, Kume, Shoen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390557/
https://www.ncbi.nlm.nih.gov/pubmed/37524826
http://dx.doi.org/10.1038/s41598-023-39712-3