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The immunosuppressive activity of myeloid-derived suppressor cells in murine Paracoccidioidomycosis relies on Indoleamine 2,3-dioxygenase activity and Dectin-1 and TLRs signaling

Paracoccidioidomycosis (PCM) is a systemic mycosis with a high incidence in Latin America. Prior studies have demonstrated the significance of the enzyme Indoleamine 2,3-dioxygenase (IDO-1) in the immune regulation of PCM as well as the vital role of myeloid-derived suppressor cells (MDSCs) in moder...

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Detalles Bibliográficos
Autores principales: Kaminski, Valéria de Lima, Preite, Nycolas Willian, Borges, Bruno Montanari, dos Santos, Bianca Vieira, Calich, Vera Lucia Garcia, Loures, Flávio Vieira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390561/
https://www.ncbi.nlm.nih.gov/pubmed/37524886
http://dx.doi.org/10.1038/s41598-023-39262-8