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Chemically programmed STING-activating nano-liposomal vesicles improve anticancer immunity

The often immune-suppressive tumor microenvironment (TME) may hinder immune evasion and response to checkpoint blockade therapies. Pharmacological activation of the STING pathway does create an immunologically hot TME, however, systemic delivery might lead to undesired off-target inflammatory respon...

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Detalles Bibliográficos
Autores principales: Chen, Xiaona, Meng, Fanchao, Xu, Yiting, Li, Tongyu, Chen, Xiaolong, Wang, Hangxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390568/
https://www.ncbi.nlm.nih.gov/pubmed/37524727
http://dx.doi.org/10.1038/s41467-023-40312-y