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Chemically programmed STING-activating nano-liposomal vesicles improve anticancer immunity
The often immune-suppressive tumor microenvironment (TME) may hinder immune evasion and response to checkpoint blockade therapies. Pharmacological activation of the STING pathway does create an immunologically hot TME, however, systemic delivery might lead to undesired off-target inflammatory respon...
Autores principales: | Chen, Xiaona, Meng, Fanchao, Xu, Yiting, Li, Tongyu, Chen, Xiaolong, Wang, Hangxiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390568/ https://www.ncbi.nlm.nih.gov/pubmed/37524727 http://dx.doi.org/10.1038/s41467-023-40312-y |
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