scRNA-seq revealed the special TCR β & α V(D)J allelic inclusion rearrangement and the high proportion dual (or more) TCR-expressing cells

Allelic exclusion, one lymphocyte expresses one antigen receptor, is a fundamental mechanism of immunological self-tolerance and highly specific immune responses to pathogens. However, the phenomenon of V(D)J allelic inclusion (incomplete allelic exclusion or allelic escape) rearrangement and dual T...

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Detalles Bibliográficos
Autores principales: Zhu, Lanwei, Peng, Qi, Li, Jun, Wu, Yingjie, Wang, Jiayi, Zhou, Dewei, Ma, Long, Yao, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390570/
https://www.ncbi.nlm.nih.gov/pubmed/37524693
http://dx.doi.org/10.1038/s41419-023-06004-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390570/
https://www.ncbi.nlm.nih.gov/pubmed/37524693
http://dx.doi.org/10.1038/s41419-023-06004-7

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