BRD4770 inhibits vascular smooth muscle cell proliferation via SUV39H2, but not EHMT2 to protect against neointima formation

The behavior of vascular smooth muscle cells (VSMCs) contributes to the formation of neointima. We previously found that EHMT2 suppressed autophagy activation in VSMCs. BRD4770, an inhibitor of EHMT2/G9a, plays a critical role in several kinds of cancers. However, whether and how BRD4770 regulates t...

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Detalles Bibliográficos
Autores principales: Chen, Tai-Qiang, Guo, Xian, Huo, Bo, Zhong, Xiao-Xuan, Wang, Qun-Hui, Chen, Yue, Zhu, Xue-Hai, Feng, Gao-Ke, Jiang, Ding-Sheng, Fang, Ze-Min, Wei, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390615/
https://www.ncbi.nlm.nih.gov/pubmed/37306883
http://dx.doi.org/10.1007/s13577-023-00924-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390615/
https://www.ncbi.nlm.nih.gov/pubmed/37306883
http://dx.doi.org/10.1007/s13577-023-00924-4

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