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BRD4770 inhibits vascular smooth muscle cell proliferation via SUV39H2, but not EHMT2 to protect against neointima formation
The behavior of vascular smooth muscle cells (VSMCs) contributes to the formation of neointima. We previously found that EHMT2 suppressed autophagy activation in VSMCs. BRD4770, an inhibitor of EHMT2/G9a, plays a critical role in several kinds of cancers. However, whether and how BRD4770 regulates t...
Autores principales: | Chen, Tai-Qiang, Guo, Xian, Huo, Bo, Zhong, Xiao-Xuan, Wang, Qun-Hui, Chen, Yue, Zhu, Xue-Hai, Feng, Gao-Ke, Jiang, Ding-Sheng, Fang, Ze-Min, Wei, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390615/ https://www.ncbi.nlm.nih.gov/pubmed/37306883 http://dx.doi.org/10.1007/s13577-023-00924-4 |
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