APEX1 Nuclease and Redox Functions are Both Essential for Adult Mouse Hematopoietic Stem and Progenitor Cells

Self-renewal and differentiation of hematopoietic stem and progenitor cells (HSPCs) are carefully controlled by extrinsic and intrinsic factors, to ensure the lifelong process of hematopoiesis. Apurinic/apyrimidinic endonuclease 1 (APEX1) is a multifunctional protein implicated in DNA repair and tra...

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Detalles Bibliográficos
Autores principales: Zaunz, Samantha, De Smedt, Jonathan, Lauwereins, Lukas, Cleuren, Lana, Laffeber, Charlie, Bajaj, Manmohan, Lebbink, Joyce H. G., Marteijn, Jurgen A., De Keersmaecker, Kim, Verfaillie, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390635/
https://www.ncbi.nlm.nih.gov/pubmed/37266894
http://dx.doi.org/10.1007/s12015-023-10550-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390635/
https://www.ncbi.nlm.nih.gov/pubmed/37266894
http://dx.doi.org/10.1007/s12015-023-10550-0

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