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Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles

The tetraspanins CD9, CD81 and CD63 are major components of extracellular vesicles (EVs). Yet, their impact on EV composition remains under‐investigated. In the MCF7 breast cancer cell line CD63 was as expected predominantly intracellular. In contrast CD9 and CD81 strongly colocalized at the plasma...

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Detalles Bibliográficos
Autores principales: Fan, Yé, Pionneau, Cédric, Cocozza, Federico, Boëlle, Pierre‐Yves, Chardonnet, Solenne, Charrin, Stéphanie, Théry, Clotilde, Zimmermann, Pascale, Rubinstein, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390663/
https://www.ncbi.nlm.nih.gov/pubmed/37525398
http://dx.doi.org/10.1002/jev2.12352