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Oxidative stress induces tau hyperphosphorylation via MARK activation in neuroblastoma N1E-115 cells
Reactive oxygen species are considered a cause of neuronal cell death in Alzheimer’s disease (AD). Abnormal tau phosphorylation is a proven pathological hallmark of AD. Microtubule affinity-regulating kinases (MARKs) regulate tau-microtubule binding and play a crucial role in neuronal survival. In t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390814/ https://www.ncbi.nlm.nih.gov/pubmed/37534088 http://dx.doi.org/10.3164/jcbn.22-39 |