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Oxidative stress induces tau hyperphosphorylation via MARK activation in neuroblastoma N1E-115 cells

Reactive oxygen species are considered a cause of neuronal cell death in Alzheimer’s disease (AD). Abnormal tau phosphorylation is a proven pathological hallmark of AD. Microtubule affinity-regulating kinases (MARKs) regulate tau-microtubule binding and play a crucial role in neuronal survival. In t...

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Detalles Bibliográficos
Autores principales: Liu, Yuhong, Chen, Yunxi, Fukui, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390814/
https://www.ncbi.nlm.nih.gov/pubmed/37534088
http://dx.doi.org/10.3164/jcbn.22-39