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Single‐cell transcriptome sequencing of B‐cell heterogeneity and tertiary lymphoid structure predicts breast cancer prognosis and neoadjuvant therapy efficacy

BACKGROUND: Breast cancer (BC) is a highly heterogeneous disease, and although immunotherapy has recently increased patient survival in a number of solid and hematologic malignancies, most BC subtypes respond poorly to immune checkpoint blockade therapy (ICB). B cells, particularly those that congre...

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Detalles Bibliográficos
Autores principales: Wang, Qing, Sun, Ke, Liu, Rui, Song, Ying, Lv, Yafeng, Bi, Pingping, Yang, Fuying, Li, Sijia, Zhao, Jiawen, Li, Xiuqin, Chen, Dong, Mei, Jialin, Yang, Rirong, Chen, Kai, Liu, Dequan, Tang, Shichong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390819/
https://www.ncbi.nlm.nih.gov/pubmed/37525587
http://dx.doi.org/10.1002/ctm2.1346